Difference between numbers for the curve effects

WouterWouter
in ACQUITY UPLC/UHPLC
Could someone explain me what is the difference between curve effect number 1 (Immediately goes to the specified conditions) and number 11 (Maintains start conditions until mext step).
What start condition is ment here? Is 1 en 11 not exactely the same thing?

Answers

  • MJSMJS
    Essentially, both start at the initial conditions of the step in the gradient.  A 1 would see an immediate, 100% change where 11 would see it delayed until the last possible second between the two rows of the gradient table.  See page 3-4 of the attached help file for the curve parameter.  It has a handy graphic.

    Generally everyone uses a 6 for most applications.  I'll use a 1 or 11 during a shutdown portion of an IM or during a cleaning cycle scenario.
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