TQD - Sample cone Problem?

manuel4146

Good days I am working with a new TQD in newborn screening (aminoacids and carnitines).The problem is that the sample cone gets dirty very much but only in the internal part (dun, like to burned).I know that normal is that the external part (cone and source) exposed to the spray gets dirty, but they are perfectly clean and polished.I attach photos.Thanks Manuel Zelaya

RD

Looks like normal "ion burn" to me.

What makes you think the cone is dirty ?

Has your sensitivity diminished ?

Does your sensitivity improve following sample cone cleaning ?

Regards,

Rich

manuel4146

Parameters of the source

Polarity     ES+

Capillary (kV) 3.5

Cone (V)     20

Extractor (V) 3

RF Lens (V)     0.3

Source Temperature (°C)     120

Desolvation Temperature (°C) 300

Cone Gas Flow (L/Hr)     10

Desolvation Gas Flow (L/Hr) 400

UPLC Flow ml/min: between 0.040 to 0.080

solvent: acetonitrile/water  grade hplc gradient

inject: 10 ul

tuning: 10 ul/min

methanol solution of aminoacid and carnitines.

thanks Manuel

Benno

I wish, I had such a neat sample cone!