Polyethylene Glycol samples on the UPLC

<p><span>We have several HPLC assays that either have PEG (polyethylene glycol) as the sample, or a component of the sample. Is it ok to run these samples with the UPLC/MS? I thought I heard in training once that PEG would build up in the system. Does anyone have experience with PEG on the UPLC? Any advice is helpful!</span></p><p><span>-Karen Birdwell</span></p>