Degasser operating pressure range?
<p>Hello, I'm relatively new to UPLC. I've been using this system about 4 months now, and recently I'm having baseline drift problem that I had not seen before. I figured when I degassed the mobile phases manually, the baseline didn't drift. Now, the in-line degasser seems to be working okay. I mean if it's not, I would have gotten some sort of warning message?? We have 3 Acquities in our lab. The degasser pressure reading on each system is:</p><p></p><p>System #1: 0.42 psi</p><p>System #2: 0.49 psi</p><p>System #3: <strong><font color="#ff0000">0.68</font></strong> psi</p><p></p><p>The #3 is the one I've been using. Although not that big difference, I was wondering the somewhat higher pressure than other 2 is an indication of ineffective degassing? I've read thru the Operator's guide and the console help, but I couldn't find any statement about degasser. What is the proper operating pressure range? How would I know if the degasser is not operating properly? Waters team, please let me know... and fellow UPLC users, what is your system's pressure reading??</p><p></p><p>(My mobile phases are water and methanol with 5%IPA, running gradient, if that makes any difference with pressure reading) </p>