How to create a CF that relates Sample Set information and Sample information.

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We are interested in creating a CF that relates Sample Set information and Sample information.
Letś say that we create a Sample Set CF ENUM (1. YES, 2. NO)
Then we are interested in creating a Sample CF that gets 1. OK when Sample Set CF is YEs and that gets 2. NO OK when Sample Set CF is NO

Will it be possible??