Which is better ACQUITY UPLC H-Class PLUS Bio System or ACQUITY UPLC I-Class PLUS
Mainly purity/aggregation analysis of purified proteins by SEC
I-class is low dispersion and can handle microbore columns 1mm if you minimize all dwell volumes and use fixed loop, also come in a flow through needle injector version. H-class has slightly higer dispersion can handle higher flow (2.2ml/min vs 2.0ml/min) probably litte more robust due to larger cappilaries. I assume you look at the binary pump versions.
The max peak or premiere version can bring considerable improvements for som analytes. I am also interested in what the difference are between bio version and premiere versions in in terms of sample and solvent compatability.0
Thank you so much for the answer.
Is the Auto•Blend Plus Technology available in the H- Class and the I class0