How many times can you sign off and lock a channel?

If a channel of a standard is acquired once, is it possible to do an endless amount of Esign1 actions on it but only lock that channel once? Am I right in thinking that once a channel is locked no more electronic signatures can be done on it? Or can you do more signatures on a locked channel but just get a warning about it to say that its locked? Any insights appreciated, thanks.
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