Quantitation of impurities
I want to quantify impurities in my sample. There are some known impurities that have been listed in the processing method. Additionally there are some unknown impurities that are not listed in the processing method as they only appered after 9 months during stability testing. In our plant, the user type "Analyst" (who perfoms the analysis) only has privileges for modify integration parameters and retention times. Is there any possibility to calculate the amount of the unknown impurities without defining them in the process method?
Thanks in advance!