Unknown Impurities Quantification
Hi, any body knows how to calculate unknowns impurities (not named at PM) if my criteria to reject peaks is based on [(Area/AverageMainPeakArea from all Stds)]*100. I made some CF's like. I have Empower 3...
CF_1 = S?.%..AVE(CCalRef1[Area]) - To get all Stds average area from main peak
CF_2 = CF_1*.0005 (to reject all areas below 0.05%) since LOQ = 0.05
Then I filter my peaks over 0.05 on the reports like: CF_2 >=0.05
My situation is that for unnamed peaks I can't get a result for CF_1.
In my processing method I'm using "RT Reference Used to Name Unnamed Peaks by RRT as my main peak). I'm trying to get the results without Naming all unknown Impurities at the PM.
My final formula is CF_3: (Amount*2200)/(REPLACE(CConst3,1))
I get results for all my peaks with CF_3 but since I'm unable to get results for unnamed peaks for CF_1 and CF_2 I can't filter peaks over/under LOQ.
Cconst3 is the RRF
Thanks in advance,