Method tranlation for changing ACN to MEOH

HelloWe just got a UPLC/Xevo TQD and I wish to stop using ACN because it is so expensive and prone to shortages.  I have found MEOH can be just as effective but it drastically changes the chromatography.  Does anyone know of a translation tool I could use that includes solvent change?TIAMike

Comments

  • Thanks Rune but for some reason I cannot see the formula.  Maybe you have a link to point me to?

    TIA

    Mike

  • I found this helpful in thinking about converting away from ACN. Hope it helps you as well!

  • Thank you sir very helpful

    Mike

  • Thank you Rune, I will try that.

    Regards
    Mike

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