resolution and S/N calculation by Empower

TCheng
TCheng
in Instrumentation and Mass Spectrometry
<p>I used to be able to obtain some documents explaining how Empower calcualte resolution and S/N from waters website. However, those docuemts are no longer available. I am wondering if someone from waters can send me those documents?</p><p></p><p>If those doucments are not available, could someone answer the following questions?</p><p></p><p>1. What are the differences between "resolution", "USP resolution" and "USP resolution HH"? I can understand the "USP resolution" and "USP resolution HH" are calculated by the peak width and peak width at 1/2 height. How about "resolution"?</p><p></p><p>2. In a lots of cases (close elute peaks) "USP resoltion" was calculated but "USP resoltion HH" was not. So the "USP resoltion" is more correct than the other? </p><p></p><p>3. When we are calculating S/N, which one we should go for "baseline noise" or "peak to peak noise" or others? </p>

Comments

  • EISING
    EISING

    Hve you tried Empower Help ??

    Look in:

    Verifying System Persformance for Resolution

    Caculating detactor noise and drift for S/N

    Best Regards

    Grethe Eising

  • rune
    rune

    Hi TCheng

    I think this is the manual you are looking for.

    Best regards

    Rune

  • TCheng
    TCheng

    Very useful information. Thanks!

  • scurran
    scurran

    I was looking for this too. Thank you.

  • BARUN
    BARUN

    thanks

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