Sirocco Plate

I know that my question is not strictly related to the community, but I'm setting up an UPLC method to perform solubility screening for discovery compounds.I'd like to use Sirocco Plates but I'd like to know which is the mesh of the membrane.Colud some one help me ?Thanks,Marco

Answers

  • Hello. The Sirocco Plate has a stack of membranes and a filter. The bigger mesh sizes are in the 1 micron range. These act like a 'screen', keeping much of the precipitate away from the surface of the filter and plugging it. The Sirocco Plate acts as a 0.45 micron filter. We tested both 0.22 micron and 0.45 micron porosities during the development of the product. We felt that the flow characteristics with 0.45 micron porosity were much better.

    I hope this information helps.

    --Doug

  • Thank you very much.

    Marco

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