Baseline Oscillation in different HPLC and different methods
Hello!We are facing a problem related to oscillation in baseline for HPLC analysis. The problem is occurring in different equipment and different methods of analysis in the same periods (and the period it happens is intermittent)… When the variation occurs the baseline presents cyclic waves. You can see some prints of the chromatograms in the pictures attached.We use Alliance HPLC, Separation Module e2695 / UV/Vis detector 2489Do you have any experience related to this kind of variation in many equipment and method at same time? Could you help me to find possible causes for the problem?