Reporting Threshold in Impurity tab
ICH defines the reporting threshold as any value ABOVE WHICH should be reported. So lest say my impurity response is Area against Main Component Area in % (Area of known or unknown impurity/Area of Main Component*100) and my method states to "report any impurities greater than or equal to 0.1%), what value do I then put into the reporting threshold in the Impurity tab of my processing method to include 0.1% and higher? If I put in 0.05 then surely Empower excludes 0.05 and only includes 0.06 onwards when it should be including 0.05 (which rounds to 0.1% and should be included)? Or does Empower see any value greater than 0.05 as 0.0500001 or 0.05098766 etc. I cant figure out how to account for this when deciding what to put into the reporting threshold column. Any ideas?